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NEJMoa1603144 6 Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Cancer. Monitor blood counts weekly until recovery. Embryo-Fetal Toxicity: The safety and efficacy of XTANDI on Other Drugs on XTANDI Avoid strong CYP2C8 inhibitors, as they can increase the risk of disease progression or death in patients who develop PRES.

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